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Mouse Anti-VSTM1 Recombinant Antibody (CBXS-3814) (CBMAB-S1085-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3814
Antibody Isotype
IgG1
Application
FC, FuncS, IP

Basic Information

Immunogen
Purified SIRL-1-hIg fusion protein in PBS
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% BSA
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Vascular Cell Adhesion Molecule 1
Introduction
V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds of protein families, including immunoglobulin light and heavy chains, several T-cells such as CD2, CD4, CD80, and CD86, myelin membrane adhesion molecules, junction adhesion molecules (JAM), tyrosine-protein kinase receptors, and the programmed cell death protein1.
Entrez Gene ID
284415
UniProt ID
Q6UX27
Alternative Names
SIRL-1; SIRL1; UNQ3033
Function
Isoform 2
Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17).
Isoform 1
Inhibitory immune receptor involved in the regulation of phagocytes.
Biological Process
Biological Process immune system process Source:UniProtKB-KW
Cellular Location
Isoform 1
Membrane
Isoform 2
Secreted
Topology
Extracellular: 17-135
Helical: 136-156
Cytoplasmic: 157-236
PTM
Isoform 2 is N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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