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Mouse Anti-VSTM1 Recombinant Antibody (CBFYA-0276) (CBMAB-X0406-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYA-0276
Antibody Isotype
IgG1
Application
FC, FuncS, IP, WB

Basic Information

Immunogen
Purified SIRL-1-hIg fusion protein in PBS
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% BSA
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Vascular Cell Adhesion Molecule 1
Introduction
VSTM1 (V-Set And Transmembrane Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cytokine activity.
Entrez Gene ID
284415
UniProt ID
Q6UX27
Alternative Names
V-Set And Transmembrane Domain Containing 1; Signal Inhibitory Receptor On Leukocytes-1; SIRL-1; V-Set And Transmembrane Domain-Containing Protein 1; OSCAR-Like Transcript-1; LAIR Homolog; UNQ3033; SIRL1
Function
Isoform 2
Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17).
Isoform 1
Inhibitory immune receptor involved in the regulation of phagocytes.
Biological Process
Biological Process immune system process Source:UniProtKB-KW
Cellular Location
Isoform 1
Membrane
Isoform 2
Secreted
Topology
Extracellular: 17-135
Helical: 136-156
Cytoplasmic: 157-236
PTM
Isoform 2 is N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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