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Rabbit Anti-VSTM1 Recombinant Antibody (104) (CBMAB-V0080-YC)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
104
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Recombinant Human VSTM1 protein (Catalog#13171-H08H)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Vascular Cell Adhesion Molecule 1
Introduction
VSTM1 is a protein coding gene. Gene Ontology (GO) annotations show that VSTM1 is related to cytokine activity.
Entrez Gene ID
284415
UniProt ID
Q6UX27
Alternative Names
V-Set And Transmembrane Domain Containing 1; Signal Inhibitory Receptor On Leukocytes-1; SIRL-1; V-Set And Transmembrane Domain-Containing Protein 1; OSCAR-Like Transcript-1; LAIR Homolog; UNQ3033; SIRL1
Function
Isoform 2
Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17).
Isoform 1
Inhibitory immune receptor involved in the regulation of phagocytes.
Biological Process
Biological Process immune system process Source:UniProtKB-KW
Cellular Location
Isoform 1
Membrane
Isoform 2
Secreted
Topology
Extracellular: 17-135
Helical: 136-156
Cytoplasmic: 157-236
PTM
Isoform 2 is N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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