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Mouse Anti-VSTM1 Recombinant Antibody (2E12) (CBMAB-A9899-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2E12
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
VSTM1 (AAI00943.1, 1 a.a. ~ 174 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Vascular Cell Adhesion Molecule 1
Entrez Gene ID
284415
UniProt ID
Q6UX27
Alternative Names
MGC119160; MGC119161; UNQ3033
Function
Isoform 2
Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17).
Isoform 1
Inhibitory immune receptor involved in the regulation of phagocytes.
Biological Process
Biological Process immune system process Source:UniProtKB-KW
Cellular Location
Isoform 1
Membrane
Isoform 2
Secreted
Topology
Extracellular: 17-135
Helical: 136-156
Cytoplasmic: 157-236
PTM
Isoform 2 is N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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