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ATOH1

This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. [provided by RefSeq]
Full Name
ATOH1
Function
Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).
Biological Process
Auditory receptor cell fate determination Source: Ensembl
Auditory receptor cell fate specification Source: Ensembl
Axon guidance Source: Ensembl
Central nervous system development Source: ProtInc
Cerebral cortex development Source: Ensembl
Inner ear morphogenesis Source: Ensembl
Negative regulation of apoptotic process Source: Ensembl
Neuron differentiation Source: GO_Central
Neuron migration Source: Ensembl
Notch signaling pathway Source: Ensembl
Positive regulation of inner ear auditory receptor cell differentiation Source: Ensembl
Positive regulation of neuron differentiation Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Transcription by RNA polymerase II Source: ProtInc
Cellular Location
Nucleus

Anti-ATOH1 antibodies

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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: 18A6
Application*: IP, WB
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3E2
Application*: WB, E
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2B1
Application*: WB, E
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 1C5
Application*: WB, E, IF
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: CBFYM-0871
Application*: E, IC, IF, WB
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A12
Application*: E, IF, WB
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F3
Application*: E, WB
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1A8
Application*: E, WB
Target: ATOH1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: BA0315
Application*: WB
Target: ATOH1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1B12
Application*: WB, E, IF
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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