EPB41 Matched Antibody Pair (380) (APMAB-380LY)

Name: EPB41 Matched Antibody Pair (380)
SKU: APMAB-380LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-EPB41 monoclonal antibody, 100 ug

Detection Antibody

Anti-EPB41 Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009]

Alternative Names

Erythrocyte Membrane Protein Band 4.1; Elliptocytosis 1, RH-Linked; Band 4.1; EPB4.1; 4.1R; P4.1;

Entrez Gene ID

2035

UniProt ID

P11171

More Infomation

References

Cao, M., Huang, Z., Zhou, H., Lin, J., & Zhang, D. (2021). Clinical and molecular genetic analysis of a Chinese family with hereditary elliptocytosis caused by a novel mutation in the EPB41 gene. Journal of Clinical Laboratory Analysis, 35(6), e23781.

Zhou, C., Huang, X., Li, X., & Xiong, Y. (2021). Circular RNA erythrocyte membrane protein band 4.1 assuages ultraviolet irradiation-induced apoptosis of lens epithelial cells by stimulating 5’-bisphosphate nucleotidase 1 in a miR-24-3p-dependent manner. Bioengineered, 12(1), 8953-8964.

Yuan, J., Xing, H., Li, Y., Song, Y., Zhang, N., Xie, M., ... & Yang, M. (2021). EPB41 suppresses the Wnt/β-catenin signaling in non-small cell lung cancer by sponging ALDOC. Cancer Letters, 499, 255-264.

Zhao, Q., Li, Y., Li, Y., Ji, X., Li, H., Wu, D., ... & Wang, X. (2020). Silencing EPB41 Gene Expression Leads to Cell Cycle Arrest, Migration Inhibition, and Upregulation of Cell Surface Antigen in DC2. 4 Cells. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 26, e920594-1.

Shin, S., Hwang, K. A., Paik, K., & Park, J. (2020). A novel EPB41 p. Trp704* mutation in a Korean patient with hereditary elliptocytosis: a case report. Hematology, 25(1), 321-326.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-EPB41 (AA 116-226) Recombinant Antibody (CBFYE-0924)

Mouse Anti-EPB41 Recombinant Antibody (A-4)

Mouse Anti-EPB41 Recombinant Antibody (CBYY-1026)

Mouse Anti-EPB41 Recombinant Antibody (CBFYE-0925)

Mouse Anti-EPB41 Recombinant Antibody (3D9)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Second antibody and isotype control

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