CBY1 Matched Antibody Pair (194) (APMAB-194LY)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-CBY1 polyclonal antibody, 100 ug

Detection Antibody

Anti-CBY1 Mouse monoclonal, IgG1 antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative Names

Chibby Family Member 1, Beta Catenin Antagonist; PKD2 Interactor, Golgi And Endoplasmic Reticulum-Associated 1; Chibby CTNNB1-Mediated Transcription Inhibitor; Cytosolic Leucine-Rich Protein; ARPP-Binding Protein; PIGEA-14; C22orf2; PGEA1; ARB1; CBY;

Entrez Gene ID

25776

UniProt ID

Q9Y3M2

More Infomation

References

Guo, L., Beck, T., Fulmer, D., Ramos‐Ortiz, S., Glover, J., Wang, C., ... & Norris, R. A. (2021). DZIP1 regulates mammalian cardiac valve development through a Cby1‐β‐catenin mechanism. Developmental Dynamics.

Wen, S., Qin, Y., Wang, R., Yang, L., Zeng, H., Zhu, P., ... & Tu, G. (2021). A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels. Cell death & disease, 12(5), 1-14.

Mancini, M., Soverini, S., Gugliotta, G., Santucci, M. A., Rosti, G., Cavo, M., ... & Castagnetti, F. (2017). Chibby 1: a new component of β-catenin-signaling in chronic myeloid leukemia. Oncotarget, 8(50), 88244.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-CBY1 Recombinant Antibody (2F2)

Mouse Anti-CBY1 Recombinant Antibody (CBFYC-0907)

Mouse Anti-CBY1 Recombinant Antibody (C2325)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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