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Mouse Anti-TRDMT1 Monoclonal Antibody (1E8) (CBMAB-0269-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1E8
Antibody Isotype
IgG2b
Application
IP, MA

Basic Information

Immunogen
Recombinant peptide (Full Length)
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TRDMT1 Gene(Protein Coding) TRNA Aspartic Acid Methyltransferase 1
Introduction
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
Entrez Gene ID
1787
UniProt ID
O14717
Alternative Names
DNMT2; RNMT1
Function
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
Biological Process
Biological Process response to amphetamine Source:Ensembl
Biological Process tRNA C5-cytosine methylation Source:GO_Central1 Publication
Biological Process tRNA methylation Source:MGI1 Publication
Biological Process tRNA modification Source:Reactome
Biological Process tRNA stabilization Source:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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