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Mouse Anti-TRDMT1 Recombinant Antibody (1E12) (CBMAB-A2333-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1E12
Antibody Isotype
IgG1, λ
Application
WB, ELISA

Basic Information

Immunogen
DNMT2 (AAH47733, 1 a.a. ~ 391 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, λ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TRDMT1 Gene(Protein Coding) TRNA Aspartic Acid Methyltransferase 1
Introduction
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Entrez Gene ID
1787
UniProt ID
O14717
Alternative Names
DNMT2; M.HsaIIP; PuMet; RNMT1
Function
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
Biological Process
Biological Process response to amphetamine Source:Ensembl
Biological Process tRNA C5-cytosine methylation Source:GO_Central1 Publication
Biological Process tRNA methylation Source:MGI1 Publication
Biological Process tRNA modification Source:Reactome
Biological Process tRNA stabilization Source:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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