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Mouse Anti-TRDMT1 Recombinant Antibody (102B1259.2) (CBMAB-D2347-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
102B1259.2
Antibody Isotype
IgG1, κ
Application
WB

Basic Information

Specificity
Human, Mouse
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TRDMT1 Gene(Protein Coding) TRNA Aspartic Acid Methyltransferase 1
Introduction
TRDMT1 is a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
Entrez Gene ID
Human1787
Mouse13434
UniProt ID
HumanO14717
MouseO55055
Alternative Names
TRNA Aspartic Acid Methyltransferase 1; DNA (Cytosine-5)-Methyltransferase-Like Protein 2; TRNA (Cytosine(38)-C(5))-Methyltransferase; DNA MTase Homolog HsaIIP; PUMET; DNMT2; DNA (Cytosine-5-)-Methyltransferase 2; TRNA (Cytosine-5-)-Methyltransferase; DNA Methyltransferase Homolog HsaIIP; DNA Cytosine-5 Methyltransferase 2;
Function
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
Biological Process
Biological Process response to amphetamine Source:Ensembl
Biological Process tRNA C5-cytosine methylation Source:GO_Central1 Publication
Biological Process tRNA methylation Source:MGI1 Publication
Biological Process tRNA modification Source:Reactome
Biological Process tRNA stabilization Source:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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