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TFPI Matched Antibody Pair (1199) (APMAB-1199LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-TFPI polyclonal antibody, 100 ug
Detection Antibody
Anti-TFPI Mouse polyclonal antibody, 40 ul
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Alternative Names
Tissue Factor Pathway Inhibitor; Extrinsic Pathway Inhibitor; Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor); TFPI1; LACI; EPI; Lipoprotein-Associated Coagulation Inhibitor; Anti-Convertin; TFI;
Entrez Gene ID
7035
UniProt ID
P10646
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For research use only. Not intended for any clinical use.

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