Search : Keywords Target

loading...

Welcome Sign in or Don't have an account?Register

TAGLN

This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]

Full Name

TAGLN Gene(Protein Coding) Transgelin

Function

Actin cross-linking/gelling protein (By similarity).
Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.

Biological Process

Biological Process epithelial cell differentiationIDA:UniProtKB1 Publication
Biological Process muscle organ developmentTAS:ProtInc1 Publication

Cellular Location

Cytoplasm

Anti-TAGLN antibodies

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-TAGLN Recombinant Antibody (CF422) (CBMAB-FT076LY)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: CF422

Application*: ELISA, WB, IHC

Mouse Anti-TAGLN Recombinant Antibody (4B11) (CBMAB-A8857-LY)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4B11

Application*: WB, E

Mouse Anti-TAGLN Recombinant Antibody (3A3) (CBMAB-A8856-LY)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3A3

Application*: WB, E

Mouse Anti-TAGLN Recombinant Antibody (1D11) (CBMAB-A8855-LY)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1D11

Application*: WB, E

Mouse Anti-TAGLN Recombinant Antibody (1C4) (CBMAB-A8854-LY)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1C4

Application*: E, E

Mouse Anti-TAGLN Recombinant Antibody (1E2) (CBMAB-A8853-LY)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1E2

Application*: WB, E

Mouse Anti-TAGLN Recombinant Antibody (SMP22a) (CBMAB-S6571-CQ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse

Clone: SMP22a

Application*: P, IF

Mouse Anti-TAGLN Recombinant Antibody (CBXS-0927) (CBMAB-S3841-CQ)

SDS

Target: TAGLN

Host: Mouse

Specificity: Human

Clone: CBXS-0927

Application*: WB, IC, P, C, E

Mouse Anti-TAGLN Recombinant Antibody (CBXS-5855) (CBMAB-S0709-CQ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Mouse, Rat

Clone: CBXS-5855

Application*: IH, WB

Mouse Anti-TAGLN Recombinant Antibody (CBXS-5828) (CBMAB-S0684-CQ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5828

Application*: E

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1915) (CBMAB-T0997-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG

Specificity: Pig, Rat, Human, Cattle, Mouse

Clone: CBYJT-1915

Application*: WB, IF, E

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1914) (CBMAB-T0996-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Pig, Rat

Clone: CBYJT-1914

Application*: E, WB, IH

Mouse Anti-TAGLN Recombinant Antibody (SPM606) (CBMAB-T0994-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Pig, Rabbit

Clone: SPM606

Application*: F, P, IF, MC

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1913) (CBMAB-T0993-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Monkey

Clone: CBYJT-1913

Application*: WB, IH, IC, IF, P

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1912) (CBMAB-T0992-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-1912

Application*: IF, P

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1911) (CBMAB-T0991-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1911

Application*: WB, IC

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1910) (CBMAB-T0990-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-1910

Application*: E

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1909) (CBMAB-T0989-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-1909

Application*: E, WB

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1908) (CBMAB-T0988-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-1908

Application*: E, WB

Mouse Anti-TAGLN Recombinant Antibody (CBYJT-1907) (CBMAB-T0987-YJ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBYJT-1907

Application*: E, WB

Mouse Anti-TAGLN Antibody (11BA42) (CBMAB-1639CQ)

SDS

Target: TAGLN

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 11BA42

Application*: E, WB

TAGLN Matched Antibody Pair (1181) (APMAB-1181LY)

SDS

Target: TAGLN

Specificity: Human

TAGLN Matched Antibody Pair (1180) (APMAB-1180LY)

SDS

Target: TAGLN

Specificity: Human

TAGLN Matched Antibody Pair (1179) (APMAB-1179LY)

SDS

Target: TAGLN

Specificity: Human

TAGLN Matched Antibody Pair (1178) (APMAB-1178LY)

SDS

Target: TAGLN

Specificity: Human

TAGLN Matched Antibody Pair (1177) (APMAB-1177LY)

SDS

Target: TAGLN

Specificity: Human

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

Online Inquiry