SDC2

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq]

syndecan 2

Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).

Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process dendrite morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of dendrite morphogenesisISS:UniProtKB

Membrane

Extracellular: 19-144
Helical: 145-169
Cytoplasmic: 170-201

O-glycosylated with core 1 or possibly core 8 glycans. Contains heparan sulfate.