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Mouse Anti-SDC2 Recombinant Antibody (1B2) (CBMAB-A7944-LY)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
1B2
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SDC2 (NP_002989.2, 32 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
syndecan 2
Introduction
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
HSPG; HSPG1; SYND2
Function
Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).
Biological Process
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process dendrite morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of dendrite morphogenesisISS:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 19-144
Helical: 145-169
Cytoplasmic: 170-201
PTM
O-glycosylated with core 1 or possibly core 8 glycans. Contains heparan sulfate.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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