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NT5E

The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Full Name
5'-Nucleotidase Ecto
Function
Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.
Biological Process
Adenosine biosynthetic processIEA:Ensembl
ADP catabolic processIEA:Ensembl
AMP catabolic processManual Assertion Based On ExperimentIBA:GO_Central
ATP metabolic processManual Assertion Based On ExperimentIDA:MGI
BiomineralizationManual Assertion Based On ExperimentIDA:MGI
Calcium ion homeostasisIEA:Ensembl
DNA metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Leukocyte cell-cell adhesionManual Assertion Based On ExperimentIDA:CACAO
Negative regulation of inflammatory responseIEA:Ensembl
Response to ATPManual Assertion Based On ExperimentIDA:MGI
Response to inorganic substanceManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Cell membrane
Involvement in disease
Calcification of joints and arteries (CALJA):
A condition characterized by adult-onset calcification of the lower extremity arteries, including the iliac, femoral and tibial arteries, and hand and foot capsule joints. Age of onset has been reported as early as the second decade of life, usually involving intense joint pain or calcification in the hands.

Anti-NT5E antibodies

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Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0173
Application*: F, C, FN, IF, IP, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLQN-002
Application*: E, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLQ5-030
Application*: WB, P, IH, F
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLQ5-007
Application*: E, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLQ5-006
Application*: F
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Horse
Clone: CBLQ5-004
Application*: F
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBLQ5-002
Application*: IH, WB
Target: NT5E
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBLQ5-001
Application*: WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AD2
Application*: F
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G6B10
Application*: WB, E, IH
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G4
Application*: WB, F
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C4-2B5
Application*: E, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 45M4F9
Application*: WB, IH, P
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 45M3B4
Application*: WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2B6
Application*: WB, E
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G2
Application*: WB, IH
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D7
Application*: E, IH, P
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-4264
Application*: WB, IC, P, IH-F, E, IP, IF, F
Target: NT5E
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBWJC-2353
Application*: F, IH
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2352
Application*: F
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0684
Application*: E, P
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C1567
Application*: WB, E, IP
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: CBYY-C1566
Application*: F, IF, C, IH
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1564
Application*: E, WB, P, IF, F
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 974CT7.5.3
Application*: WB, P, E
Target: NT5E
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-3017
Application*: F
Target: NT5E
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-3016
Application*: WB, P
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-3015
Application*: WB, IC, IF
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-3014
Application*: E, IH, P
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0046
Application*: F
Target: NT5E
Host: Mouse
Specificity: Human
Clone: P2B6AT
Application*: E, WB
Target: NT5E
Host: Rabbit
Specificity: Human, Mouse, Rat
Clone: D7F9A
Application*: WB, P
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBWJN-0554
Application*: WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBWJN-0553
Application*: IH, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0500
Application*: WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0412
Application*: E, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0152
Application*: E, IH
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0024
Application*: E, IH, WB
Target: NT5E
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: A1401
Application*: FC, IHC
Target: NT5E
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CAP955
Application*: ICC, IHC, IP, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP954
Application*: ICC, IHC, IP, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB324
Application*: IF, FC
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB323
Application*: IF, FC
Target: NT5E
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBR054F
Application*: WB, IHC, ICC, IHC-IF
Target: NT5E
Host: Mouse
Specificity: Human
Clone: IHC073
Application*: IH
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4D3-2C10
Application*: WB, E
Target: NT5E
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: TY/23
Application*: F
Target: NT5E
Host: Mouse
Specificity: Human
Clone: AA60-E3-3
Application*: IF, IP, WB
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 8D10G7
Application*: WB, E, IP
Target: NT5E
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 7G2
Application*: IP, C, P, F, IC/IF
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: 5F/B9
Application*: F, IF, C, IH
Target: NT5E
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 23-9
Application*: F
Target: NT5E
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 102
Application*: E
Target: NT5E
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 001
Application*: WB, P
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 07
Application*: F
Target: NT5E
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb264
Application*: FC, IHC-F, FuncS, IF, IP, WB
Target: NT5E
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: TY/23
Application*: B
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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