NAPA

This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene.

Full Name

NSF attachment protein alpha

Function

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).

Biological Process

Apical protein localization Source: Ensembl
Brain development Source: Ensembl
Intracellular protein transport Source: GO_Central
Intra-Golgi vesicle-mediated transport Source: ProtInc
Membrane fusion Source: ProtInc
Neuron differentiation Source: Ensembl
Regulation of synaptic vesicle priming Source: GO_Central
SNARE complex disassembly Source: GO_Central
Synaptic transmission, glutamatergic Source: GO_Central
Synaptic vesicle priming Source: Ensembl

Cellular Location

Cell membrane

Anti-NAPA antibodies

Mouse Anti-NAPA Recombinant Antibody (15D4) (CBMAB-1609-CN)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Cattle

Clone: 15D4

Application*: F, IC, IF, P, IP, WB

Mouse Anti-NAPA Recombinant Antibody (CBXS-0979) (CBMAB-S3886-CQ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-0979

Application*: E, WB

Mouse Anti-NAPA Recombinant Antibody (CBXS-0978) (CBMAB-S3885-CQ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat, Cattle, Dog, Hamster

Clone: CBXS-0978

Application*: WB, P, IP

Mouse Anti-NAPA Recombinant Antibody (CBXS-5041) (CBMAB-S2262-CQ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Cattle, Human, Rat

Clone: CBXS-5041

Application*: IP, WB

Mouse Anti-NAPA Recombinant Antibody (CBXS-3753) (CBMAB-S1026-CQ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Cattle, Chicken, Human, Rat

Clone: CBXS-3753

Application*: WB

Mouse Anti-NAPA Recombinant Antibody (CBXS-5800) (CBMAB-S0657-CQ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Cattle, Dog

Clone: CBXS-5800

Application*: WB, IH, IP, P

Mouse Anti-NAPA Recombinant Antibody (CBWJN-0455) (CBMAB-N1158-WJ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Cattle, Dog, Hamster, Human, Mouse, Rat

Clone: CBWJN-0455

Application*: P, IP, WB

Mouse Anti-NAPA Recombinant Antibody (CBWJN-0385) (CBMAB-N1157-WJ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat, Cattle

Clone: CBWJN-0385

Application*: WB

Mouse Anti-NAPA Recombinant Antibody (CBWJN-0384) (CBMAB-N1156-WJ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Cattle, Human, Rat

Clone: CBWJN-0384

Application*: IP, WB

Mouse Anti-NAPA Recombinant Antibody (16D1) (CBMAB-N1155-WJ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Cattle, Chicken, Human, Mouse, Rat

Clone: 16D1

Application*: IA, WB

Mouse Anti-NAPA Recombinant Antibody (4E204) (CBMAB-N1153-WJ)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Cattle, Dog, Chicken, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep

Clone: 4E204

Application*: IP, WB

Mouse Anti-NAPA Recombinant Antibody (CBYC-A1009) (CBMAB-A4602-YC)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBYC-A1009

Application*: IP, IH, WB

Mouse Anti-NAPA Recombinant Antibody (CBYC-A1008) (CBMAB-A4601-YC)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Rat, Cattle

Clone: CBYC-A1008

Application*: E, IP, WB

Mouse Anti-NAPA Recombinant Antibody (4E4) (CBMAB-A4599-YC)

Datasheet

SDS

Target: NAPA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat

Clone: 4E4

Application*: E, IP, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)