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Mouse Anti-NAPA Recombinant Antibody (CBYC-A1009) (CBMAB-A4602-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYC-A1009
Antibody Isotype
IgG
Application
IP, IHC, WB

Basic Information

Immunogen
Recombinant bovine alpha-SNAP
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid in 100 mM PMSF, 50% glycerol
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NSF attachment protein alpha
Introduction
NAPA is a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completio
Entrez Gene ID
Human8775
Mouse108124
Rat140673
UniProt ID
HumanP54920
MouseQ9DB05
RatP54921
Alternative Names
NSF Attachment Protein Alpha; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Alpha; SNAPA; N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha; Alpha Soluble NSF Attachment Protein; Alpha-Soluble NSF Attachment Protein; Alpha SNAP; Alpha-SNA
Function
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).
Biological Process
Apical protein localization Source: Ensembl
Brain development Source: Ensembl
Intracellular protein transport Source: GO_Central
Intra-Golgi vesicle-mediated transport Source: ProtInc
Membrane fusion Source: ProtInc
Neuron differentiation Source: Ensembl
Regulation of synaptic vesicle priming Source: GO_Central
SNARE complex disassembly Source: GO_Central
Synaptic transmission, glutamatergic Source: GO_Central
Synaptic vesicle priming Source: Ensembl
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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