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Mouse Anti-NAPA Recombinant Antibody (4E204) (CBMAB-N1153-WJ)


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Summary

Host Animal
Mouse
Specificity
Cattle, Dog, Chicken, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Clone
4E204
Antibody Isotype
IgG1, κ
Application
IP, WB

Basic Information

Specificity
Cattle, Dog, Chicken, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2, 0.1mM PMSF, 50% glycerol
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NSF attachment protein alpha
Introduction
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
Entrez Gene ID
Human8775
Mouse108124
Rat140673
Cattle518407
Dog612960
Chicken100858304
Hamster101829491
Monkey717355
Pig100515953
Rabbit100353882
Sheep101119072
UniProt ID
HumanP54920
MouseQ9DB05
RatP54921
CattleP81125
DogE2RQE7
ChickenA0A1D5NUZ0
HamsterA0A1U8CYN1
MonkeyF6Z9A6
PigF1RLB6
RabbitG1SEF8
SheepW5PNM6
Alternative Names
NSF Attachment Protein Alpha; N-Ethylmaleimide-Sensitive Factor Attachment Protein, Alpha; SNAPA; N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha; Alpha Soluble NSF Attachment Protein; Alpha-Soluble NSF Attachment Protein; Alpha SNAP; Alpha-SNAP; SNAP-Alpha;
Function
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).
Biological Process
Apical protein localization Source: Ensembl
Brain development Source: Ensembl
Intracellular protein transport Source: GO_Central
Intra-Golgi vesicle-mediated transport Source: ProtInc
Membrane fusion Source: ProtInc
Neuron differentiation Source: Ensembl
Regulation of synaptic vesicle priming Source: GO_Central
SNARE complex disassembly Source: GO_Central
Synaptic transmission, glutamatergic Source: GO_Central
Synaptic vesicle priming Source: Ensembl
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

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