GALK1

Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population.

Full Name

galactokinase 1

Function

Major enzyme for galactose metabolism.

Biological Process

Galactitol metabolic process Source: Ensembl
Galactose catabolic process Source: Reactome
Galactose metabolic process Source: UniProtKB
Glycolytic process from galactose Source: Ensembl

Cellular Location

Cytosol; Extracellular exosome; Cytoplasm; Membrane

Involvement in disease

Galactosemia 2 (GALAC2):
A form of galactosemia, an inborn error of galactose metabolism typically manifesting in the neonatal period, after ingestion of galactose, with jaundice, hepatosplenomegaly, hepatocellular insufficiency, food intolerance, hypoglycemia, renal tubular dysfunction, muscle hypotonia, sepsis and cataract. GALAC2 inheritance is autosomal recessive.

Anti-GALK1 antibodies

Mouse Anti-GALK1 Recombinant Antibody (CBFYH-0230) (CBMAB-H1101-FY)

Datasheet

SDS

Target: GALK1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYH-0230

Application*: E, EC, WB

Mouse Anti-GALK1 (AA 181-279) Recombinant Antibody (CBFYH-0229) (CBMAB-H1100-FY)

Datasheet

SDS

Target: GALK1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYH-0229

Application*: E, WB

Rabbit Anti-GALK1 Recombinant Antibody (EG1280) (CBMAB-EN1544-LY)

Datasheet

SDS

Target: GALK1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1280

Application*: WB: 1:500~1:1000 ELISA: 1:10000

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)