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Mouse Anti-GALK1 Recombinant Antibody (CBFYH-0230) (CBMAB-H1101-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-0230
Antibody Isotype
IgG2b, κ
Application
ELISA, ELISA(Cap), WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
galactokinase 1
Introduction
Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population.
Entrez Gene ID
2584
UniProt ID
P51570
Alternative Names
Galactokinase 1; Galactose Kinase; EC 2.7.1.6; GALK; Epididymis Secretory Protein Li 19; Galactokinase; HEL-S-19; GK1
Function
Major enzyme for galactose metabolism.
Biological Process
Galactitol metabolic process Source: Ensembl
Galactose catabolic process Source: Reactome
Galactose metabolic process Source: UniProtKB
Glycolytic process from galactose Source: Ensembl
Cellular Location
Cytosol; Extracellular exosome; Cytoplasm; Membrane
Involvement in disease
Galactosemia 2 (GALAC2):
A form of galactosemia, an inborn error of galactose metabolism typically manifesting in the neonatal period, after ingestion of galactose, with jaundice, hepatosplenomegaly, hepatocellular insufficiency, food intolerance, hypoglycemia, renal tubular dysfunction, muscle hypotonia, sepsis and cataract. GALAC2 inheritance is autosomal recessive.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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