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Rabbit Anti-GALK1 Recombinant Antibody (EG1280) (CBMAB-EN1544-LY)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1280
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:10000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from N-terminal of human GALK1.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
galactokinase 1
Introduction
Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population.
Entrez Gene ID
Human2584
Mouse14635
Rat287835
UniProt ID
HumanP51570
MouseQ9R0N0
RatQ5RKH2
Alternative Names
GK1; GALK; HEL-S-19
Function
Major enzyme for galactose metabolism.
Biological Process
Galactitol metabolic process Source: Ensembl
Galactose catabolic process Source: Reactome
Galactose metabolic process Source: UniProtKB
Glycolytic process from galactose Source: Ensembl
Cellular Location
Cytosol; Extracellular exosome; Cytoplasm; Membrane
Involvement in disease
Galactosemia 2 (GALAC2):
A form of galactosemia, an inborn error of galactose metabolism typically manifesting in the neonatal period, after ingestion of galactose, with jaundice, hepatosplenomegaly, hepatocellular insufficiency, food intolerance, hypoglycemia, renal tubular dysfunction, muscle hypotonia, sepsis and cataract. GALAC2 inheritance is autosomal recessive.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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