ELF2

ELF2 (E74 Like ETS Transcription Factor 2) is a Protein Coding gene. Diseases associated with ELF2 include Peroneal Neuropathy and Nerve Compression Syndrome. Among its related pathways are Immune response IL-23 signaling pathway and ADP signalling through P2Y purinoceptor 12. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ELF1.

ELF2

Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.

Isoform 2 may function in repression of RUNX1-mediated transactivation.

Cell differentiation Source: GO_Central
Negative regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: UniProtKB

Nucleus