CRYZ

CRYZ (Crystallin Zeta) is a Protein Coding gene. Diseases associated with CRYZ include Cardiomyopathy, Familial Hypertrophic, 2 and Danubian Endemic Familial Nephropathy. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and mRNA 3-UTR binding. An important paralog of this gene is VAT1L.

Crystallin Zeta

Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.

Protein homotetramerization Source: UniProtKB
Visual perception Source: ProtInc
Xenobiotic catabolic process Source: UniProtKB

Cytoplasm