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Rabbit Anti-CRYZ Recombinant Antibody (CBWJC-3150) (CBMAB-C4337WJ)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBWJC-3150
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Crystallin Zeta
Introduction
CRYZ (Crystallin Zeta) is a Protein Coding gene. Diseases associated with CRYZ include Cardiomyopathy, Familial Hypertrophic, 2 and Danubian Endemic Familial Nephropathy. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and mRNA 3-UTR binding. An important paralog of this gene is VAT1L.
Entrez Gene ID
1429
UniProt ID
Q08257
Alternative Names
Crystallin Zeta; EC 1.6.5.5; Crystallin, Zeta (Quinone Reductase); NADPH:Quinone Reductase; Zeta-Crystallin;
Function
Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
Biological Process
Protein homotetramerization Source: UniProtKB
Visual perception Source: ProtInc
Xenobiotic catabolic process Source: UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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