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CNTF

CNTF (Ciliary Neurotrophic Factor) is a Protein Coding gene. Diseases associated with CNTF include Motor Neuron Disease and Epilepsy, Familial Temporal Lobe, 2. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include growth factor activity and ciliary neurotrophic factor receptor binding.
Full Name
Ciliary Neurotrophic Factor
Function
CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Biological Process
Astrocyte activation Source: GO_Central
Ciliary neurotrophic factor-mediated signaling pathway Source: BHF-UCL
Cytokine-mediated signaling pathway Source: Reactome
Muscle organ morphogenesis Source: Ensembl
Negative regulation of neuron apoptotic process Source: BHF-UCL
Negative regulation of photoreceptor cell differentiation Source: Ensembl
Neuron development Source: Ensembl
Positive regulation of axon regeneration Source: GO_Central
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of gene expression Source: MGI
Positive regulation of tyrosine phosphorylation of STAT protein Source: BHF-UCL
Regulation of retinal cell programmed cell death Source: Ensembl
Signal transduction Source: ProtInc
Cellular Location
Cytoplasm

Anti-CNTF antibodies

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Target: CNTF
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: C11081
Application*: WB, N
Target: CNTF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: CBCNC-038
Application*: WB
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C4008
Application*: E, IP, WB
Target: CNTF
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-1019
Application*: WB, N, E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG3
Specificity: Rat
Clone: CBYY-C2958
Application*: E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2956
Application*: E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-C0033
Application*: WB, IP, IF, E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0032
Application*: WB, IP, IF, E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-2012
Application*: WB, IP, IF, E
Target: CNTF
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-2009
Application*: WB, IP, IF, E, P
Target: CNTF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-2008
Application*: WB, IP, IF, E
Target: CNTF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 121
Application*: E
Target: CNTF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 1
Application*: E
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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