CEACAM16

The protein encoded by this gene is a secreted glycoprotein that in mouse interacts with tectorial membrane proteins in the inner ear. The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range. Defects in this gene likely are a cause of non-syndromic autosomal dominant hearing loss. [provided by RefSeq, May 2012]

Carcinoembryonic Antigen Related Cell Adhesion Molecule 16

Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.

Sensory perception of sound Source: UniProtKB

Secreted. Localizes to the tip of cochlear outer hair cells and to the tectorial membrane.

Deafness, autosomal dominant, 4B (DFNA4B): A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
Deafness, autosomal recessive, 113 (DFNB113): A form of non-syndromic, sensorineural deafness characterized by postlingual progressive hearing impairment. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.