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HHEX Matched Antibody Pair (539) (APMAB-539LY)


See all HHEX antibodies
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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-HHEX monoclonal, IgG2b antibody, 100 ug
Detection Antibody
Anti-HHEX Biotinylated mouse monoclonal, IgG2a antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. [provided by RefSeq, Jul 2008]
Alternative Names
Hematopoietically Expressed Homeobox; Homeobox Protein HEX; Homeobox Protein PRH; PRHX; HEX; PRH;
Entrez Gene ID
3087
UniProt ID
Q03014
More Infomation

Watanabe, H., Okada, H., Hirose, J., Omata, Y., Matsumoto, T., Matsumoto, M., ... & Tanaka, S. (2022). Transcription Factor Hematopoietically Expressed Homeobox Protein (Hhex) Negatively Regulates Osteoclast Differentiation by Controlling Cyclin‐Dependent Kinase Inhibitors. JBMR plus, 6(4), e10608.

González-Jiménez, A., López-Cotarelo, P., Agudo-Jiménez, T., Martínez-Ginés, M., García-Domínguez, J. M., Urcelay, E., & Espino-Paisán, L. (2022). Unraveling the Influence of HHEX Risk Polymorphism rs7923837 on Multiple Sclerosis Pathogenesis. International Journal of Molecular Sciences, 23(14), 7956.

Guo, Y., Zhu, Z., Huang, Z., Cui, L., Yu, W., Hong, W., ... & Liu, C. Y. (2022). CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis. Nature communications, 13(1), 4995.

Evseeva, M. N., Dyikanov, D. T., Karagyaur, M. N., Prikazchikova, T. A., Sheptulina, A. F., Balashova, M. S., ... & Kulebyakin, K. Y. (2021). Hematopoietically-expressed homeobox protein HHEX regulates adipogenesis in preadipocytes. Biochimie, 185, 68-77.

Starczynowski, D. T. (2020). HHEX expression drives AML development. Blood, The Journal of the American Society of Hematology, 136(14), 1575-1576.

Laidlaw, B. J., Duan, L., Xu, Y., Vazquez, S. E., & Cyster, J. G. (2020). The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development. Nature immunology, 21(9), 1082-1093.

Galavi, H., Mollashahee‐Kohkan, F., Saravani, R., Sargazi, S., Noorzehi, N., & Shahraki, H. (2019). HHEX gene polymorphisms and type 2 diabetes mellitus: A case‐control report from Iran. Journal of cellular biochemistry, 120(10), 16445-16451.

Jang, S. W., Hwang, S. S., Kim, H. S., Kim, M. K., Lee, W. H., Hwang, S. U., ... & Lee, G. R. (2019). Homeobox protein Hhex negatively regulates Treg cells by inhibiting Foxp3 expression and function. Proceedings of the National Academy of Sciences, 116(51), 25790-25799.

Lu, C. C., Chen, Y. T., Chen, S. Y., Hsu, Y. M., Lin, C. C., Tsao, J. W., ... & Tsai, F. J. (2018). Hematopoietically expressed homeobox gene is associated with type 2 diabetes in KK Cg‑Ay/J mice and a Taiwanese Han Chinese population. Experimental and Therapeutic Medicine, 16(1), 185-191.

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For research use only. Not intended for any clinical use.

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