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FGF19 Matched Antibody Pair (431) (APMAB-431LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-FGF19 monoclonal antibody, 100 ug
Detection Antibody
Anti-FGF19 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008]
Alternative Names
Fibroblast Growth Factor 19; FGF-19;
Entrez Gene ID
9965
UniProt ID
O95750
More Infomation

Chrysavgis, L., Giannakodimos, I., Chatzigeorgiou, A., Tziomalos, K., Papatheodoridis, G., & Cholongitas, E. (2022). The role of fibroblast growth factor 19 in the pathogenesis of nonalcoholic fatty liver disease. Expert Review of Gastroenterology & Hepatology, 16(9), 835-849.

Ursic-Bedoya, J., Chavey, C., Desandré, G., Meunier, L., Dupuy, A. M., Reyes, I. G. D., ... & Gregoire, D. (2022). Fibroblast growth factor 19 stimulates water intake. Molecular Metabolism, 60, 101483.

Liu, T., Tang, X., Cui, Y., Xiong, X., Xu, Y., Hu, S., ... & Wang, C. (2022). Fibroblast growth factor 19 improves LPS-induced lipid disorder and organ injury by regulating metabolomic characteristics in mice. Oxidative Medicine and Cellular Longevity, 2022.

Mohamed, G. A., Nashaat, E. H., Fawzy, H. M., & ElGhandour, A. M. (2022). Assessment of fibroblast growth factor 19 as a non-invasive serum marker for hepatocellular carcinoma. World Journal of Hepatology, 14(3), 623.

Chen, H., Li, J., Zhang, D., Zhou, X., & Xie, J. (2021). Role of the fibroblast growth factor 19 in the skeletal system. Life Sciences, 265, 118804.

Chen, Z., Jiang, L., Liang, L., Koral, K., Zhang, Q., Zhao, L., ... & Tao, J. (2021). The role of fibroblast growth factor 19 in hepatocellular carcinoma. The American Journal of Pathology, 191(7), 1180-1192.

Zhou, Y., Yang, L., Bo, C., Zhang, X., Zhang, J., & Li, Y. (2021). MicroRNA-9-3p Aggravates Cerebral Ischemia/Reperfusion Injury by Targeting Fibroblast Growth Factor 19 (FGF19) to Inactivate GSK-3β/Nrf2/ARE Signaling. Neuropsychiatric Disease and Treatment, 17, 1989.

Guo, A., Li, K., & Xiao, Q. (2020). Fibroblast growth factor 19 alleviates palmitic acid-induced mitochondrial dysfunction and oxidative stress via the AMPK/PGC-1α pathway in skeletal muscle. Biochemical and Biophysical Research Communications, 526(4), 1069-1076.

Maeda, T., Kanzaki, H., Chiba, T., Ao, J., Kanayama, K., Maruta, S., ... & Kato, N. (2019). Serum fibroblast growth factor 19 serves as a potential novel biomarker for hepatocellular carcinoma. BMC cancer, 19(1), 1-9.

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For research use only. Not intended for any clinical use.

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