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Mouse Anti-CALB1 Recombinant Antibody (CB-955) (CBMAB-1271-CN)


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Summary

Host Animal
Mouse
Specificity
Cattle, Mouse, Rat, Human
Clone
CB-955
Antibody Isotype
IgG1
Application
IH, IF, WB

Basic Information

Immunogen
Bovine kidney calbindin-D.
Host Species
Mouse
Specificity
Cattle, Mouse, Rat, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB0.5-1 µg/ml
IF(ICC)2 µg/ml
IHC1-2 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
1.2% sodium acetate, 2 mg BSA
Preservative
0.01% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Calbindin 1
Introduction
The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. The protein may stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
Entrez Gene ID
Human793
Mouse12307
Rat83839
Sheep101114786
Rabbit100008818
Goat102191539
Guinea pig100732072
Cat101100617
Cattle539930
Pig100153645
UniProt ID
HumanP05937
MouseP12658
RatP07171
SheepW5PKW1
GoatA0A452FGU7
Guinea pigH0UUB7
CatA0A337RZZ8
CattleP04467
PigB3VFB6
Alternative Names
calbindin; D-28K; calbindin 1, 28kDa; calbindin D28; vitamin D-dependent calcium-binding protein, avian-type
Function
Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
Biological Process
Amyloid fibril formation Source: Reactome
Cellular response to organic substance Source: Ensembl
Cochlea development Source: Ensembl
Locomotory behavior Source: Ensembl
Long-term memory Source: UniProtKB
Metanephric collecting duct development Source: Ensembl
Metanephric connecting tubule development Source: Ensembl
Metanephric distal convoluted tubule development Source: Ensembl
Metanephric part of ureteric bud development Source: Ensembl
Regulation of cytosolic calcium ion concentration Source: GO_Central
Regulation of long-term synaptic potentiation Source: GO_Central
Regulation of presynaptic cytosolic calcium ion concentration Source: GO_Central
Retina layer formation Source: Ensembl
Short-term memory Source: UniProtKB
Cellular Location
Cuticular plate; Cytosol; Postsynaptic cytosol; Presynaptic cytosol; Extracellular exosome; Nucleus; Axon; Calyx of Held; Dendrite; Dendritic spine; GABA-ergic synapse; Glutamatergic synapse; Hippocampal mossy fiber to CA3 synapse; Neuron projection; Neuronal cell body; Stereocilium; Synapse; Terminal bouton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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