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TARBP2 Matched Antibody Pair (1184) (APMAB-1184LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-TARBP2 polyclonal antibody, 100 ug
Detection Antibody
Anti-TARBP2 Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
Alternative Names
TARBP2, RISC Loading Complex RNA Binding Subunit; TAR (HIV-1) RNA Binding Protein 2; TRBP; Trans-Activation Responsive RNA-Binding Protein; Trans-Activation-Responsive RNA-Binding Protein; RISC-Loading Complex Subunit TARBP2; TAR (HIV) RNA-Binding Protein TRBP1;
Entrez Gene ID
6895
UniProt ID
Q15633
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For research use only. Not intended for any clinical use.

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