ZFAND6

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of Lys-48-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).

ZFAND6

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cellular response to tumor necrosis factor Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process protein targeting to peroxisome Source:UniProtKB
Biological Process regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication

Cytoplasm