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VCAM1

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
Full Name
Vascular Cell Adhesion Molecule 1
Function
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Biological Process
Biological Process acute inflammatory response Source:Ensembl
Biological Process aging Source:Ensembl
Biological Process amine metabolic process Source:UniProtKB1 Publication
Biological Process B cell differentiation Source:BHF-UCL1 Publication
Biological Process calcium-mediated signaling using intracellular calcium Source Source:UniProtKB1 Publication
Biological Process cardiac neuron differentiation Source:Ensembl
Biological Process cell adhesion Source:BHF-UCL1 Publication
Biological Process cell chemotaxis Source:Ensembl
Biological Process cell-cell adhesion in response to extracellular stimulus Source:ARUK-UCL1 Publication
Biological Process cell-matrix adhesion Source:UniProtKB1 Publication
Biological Process cellular response to amyloid-beta Source:ARUK-UCL1 Publication
Biological Process cellular response to tumor necrosis factor Source:Ensembl
Biological Process cellular response to vascular endothelial growth factor stimulus Source:Ensembl
Biological Process chronic inflammatory response Source:Ensembl
Biological Process heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source:BHF-UCL1 Publication
Biological Process heterotypic cell-cell adhesion Source:ARUK-UCL1 Publication
Biological Process innervation Source:Ensembl
Biological Process leukocyte cell-cell adhesion Source:BHF-UCL3 Publications
Biological Process leukocyte tethering or rolling Source:UniProtKB1 Publication
Biological Process membrane to membrane docking Source:BHF-UCL1 Publication
Biological Process positive regulation of T cell proliferation Source:BHF-UCL1 Publication
Biological Process response to ethanol Source:Ensembl
Biological Process response to hypoxia Source:Ensembl
Biological Process response to ionizing radiation Source:Ensembl
Biological Process response to lipopolysaccharide Source:Ensembl
Biological Process response to nicotine Source:Ensembl
Biological Process response to nutrient Source:Ensembl
Biological Process response to zinc ion Source:Ensembl
Cellular Location
Membrane
Topology
Extracellular: 25-698
Helical: 699-720
Cytoplasmic: 721-739
PTM
Sialoglycoprotein.

Anti-VCAM1 antibodies

+ Filters
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Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1354
Application*: WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: MR106
Application*: F
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: A1438
Application*: Neu, IF
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1437
Application*: FC
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF470
Application*: ELISA, WB, IHC
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CB141A
Application*: ELISA, WB, IHC
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CB386
Application*: IF, FC
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CB385
Application*: IF, FC
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CB384
Application*: IF, FC
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBAb243
Application*: WB, IH, IF, IP
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: D8U5V
Application*: WB, IP, IF, IF (IC), F
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: D2T4N
Application*: WB, P
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: E1E8X
Application*: WB, IP, F
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5H4-B9
Application*: F
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: UJ127
Application*: IF/IC, C
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM275
Application*: IF/IC, C
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: P3C4
Application*: IH, IP, IF, F
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: MK2
Application*: F
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-N8
Application*: E-detection
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-K9
Application*: FC
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: BBIG-V3
Application*: FC
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3B10
Application*: E, WB
Target: VCAM1
Host: Sheep
Specificity: Human
Clone: 12G8
Application*: E, DB, IH, WB
Target: VCAM1
Host: Sheep
Specificity: Human
Clone: 12G7
Application*: E, DB, IH, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E8
Application*: WB, IH
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: CBYY-1353
Application*: WB, F
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: CBYY-1352
Application*: WB, IH, IF
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1351
Application*: WB, IH, IF
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1350
Application*: WB, IF, F
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-1349
Application*: F, IF, P
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-1348
Application*: E
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1347
Application*: F
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1346
Application*: WB, IP, IC
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-1345
Application*: F, IF
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-1344
Application*: WB, IH, IP, P
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-1342
Application*: F, FS, IF, IP
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1341
Application*: F, IC, IH, IP, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYY-1340
Application*: E, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1339
Application*: E, WB, IH
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-1338
Application*: IH, IP, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1337
Application*: IH, WB
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-1336
Application*: F, IH, IP
Target: VCAM1
Host: Mouse
Specificity: Human
Clone: CBYY-1335
Application*: E, IC, IH, WB
Target: VCAM1
Host: Mouse
Specificity: Human
Clone: CBYY-1334
Application*: E, IC, IH, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1333
Application*: E, IH, WB
Target: VCAM1
Host: Mouse
Specificity: Human
Clone: CBYY-1332
Application*: C
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-1331
Application*: IP, I, IF
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1330
Application*: E, F, IH
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1329
Application*: E, WB, IH
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1328
Application*: WB, IH
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-1327
Application*: WB, IH, IP
Target: VCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-1326
Application*: WB, E
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-1325
Application*: WB
Target: VCAM1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-1324
Application*: F, IH, IP, C
Target: VCAM1
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: CBYY-1323
Application*: WB, C, IC, IH
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYY-1322
Application*: E
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYY-1321
Application*: E
Target: VCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: MVCAM.A(429)
Application*: F, C
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1.4C3
Application*: F, P, IF
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: BA0276
Application*: F, IF, C, P, IP, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: VCAM1/843
Application*: P
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rabbit
Clone: 6G9
Application*: E, P, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: STA
Application*: F
Target: VCAM1
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: 324
Application*: IC, P, C, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G11B1
Application*: IP, C, F
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: M/K-2
Application*: FN, IF, C, IP
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: BA0275
Application*: IP, WB
Target: VCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: BA0160
Application*: IP, WB
Target: VCAM1
Host: Sheep
Specificity: Human
Clone: 12G6
Application*: E, DB, IH, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B534
Application*: FC, IP
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A518 (1G11B1)
Application*: FC, IH, IP
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1814
Application*: E, FC, IH, IP
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: CBYY-C3266
Application*: WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2036
Application*: F, IH
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-C2035
Application*: F, IP, IF, FN, C
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2034
Application*: IH
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2033
Application*: IF, F, IP, C, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0589
Application*: F
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0457
Application*: E, F, IH, WB
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: CBYY-C0439
Application*: F, IH, IP, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0308
Application*: F, C
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H101
Application*: F
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6D43
Application*: F, IH
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5K267
Application*: E, F, C, WB
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: 5K220
Application*: F, IF, IH, IP
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5G69
Application*: IH
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-186965
Application*: IC/IF, F, IP, C, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: 3H10
Application*: WB
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: 2Q676
Application*: IF, IH, IP
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2Q666
Application*: F, IH
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2C11
Application*: WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1H6
Application*: E, WB
Target: VCAM1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 13A29
Application*: F, IF, IH, IP
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 51-10C9
Application*: F, C
Target: VCAM1
Host: sheep
Antibody Isotype: IgG
Specificity: Human
Clone: 12G9
Application*: E, DB, C, WB
Target: VCAM1
Host: sheep
Antibody Isotype: IgG
Specificity: Human
Clone: 12G10
Application*: E, DB, C, WB
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1299.27-1
Application*: C
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B532
Application*: E, IH, IP
Target: VCAM1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: 429
Application*: C, FN, C, IP, N
Target: VCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Pig, Monkey, Human
Clone: 1.G11B1
Application*: C, E, WB, P, F, IF, FN
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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