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TNFRSF19

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Full Name

TNFRSF19 Gene(Protein Coding) TNF Receptor Superfamily Member 19

Function

Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.

Biological Process

Biological Process apoptotic process Source:UniProtKB1 Publication
Biological Process hair follicle development Source:Ensembl
Biological Process JNK cascade Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:GO_Central1 Publication
Biological Process positive regulation of JNK cascade Source:GO_Central1 Publication

Cellular Location

Membrane

Topology

Extracellular: 30-170
Helical: 171-191
Cytoplasmic: 192-423

Anti-TNFRSF19 antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-TNFRSF19 Recombinant Antibody (1H6) (CBMAB-A9302-LY)

SDS

Target: TNFRSF19

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1H6

Application*: WB, E

Mouse Anti-Tnfrsf19 Recombinant Antibody (CBYJT-3792) (CBMAB-T3176-YJ)

SDS

Target: TNFRSF19

Host: Mouse

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBYJT-3792

Application*: WB, IP, IF, E

Rat Anti-Tnfrsf19 Recombinant Antibody (CBYJT-3791) (CBMAB-T3175-YJ)

SDS

Target: Tnfrsf19

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBYJT-3791

Application*: WB

Rabbit Anti-Tnfrsf19 Recombinant Antibody (CBYJT-3790) (CBMAB-T3174-YJ)

SDS

Target: Tnfrsf19

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBYJT-3790

Application*: E, WB

Rabbit Anti-Tnfrsf19 Recombinant Antibody (CBYJT-3789) (CBMAB-T3173-YJ)

SDS

Target: Tnfrsf19

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBYJT-3789

Application*: EC

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3785) (CBMAB-T3169-YJ)

SDS

Target: TNFRSF19

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-3785

Application*: WB, IP, IF, E

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3784) (CBMAB-T3168-YJ)

SDS

Target: TNFRSF19

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3784

Application*: F, MC

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3783) (CBMAB-T3167-YJ)

SDS

Target: TNFRSF19

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3783

Application*: F, MC

Rat Anti-TNFRSF19 Recombinant Antibody (CBYJT-3782) (CBMAB-T3166-YJ)

SDS

Target: TNFRSF19

Host: Rat

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-3782

Application*: F

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3781) (CBMAB-T3165-YJ)

SDS

Target: TNFRSF19

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-3781

Application*: E, WB

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3780) (CBMAB-T3164-YJ)

SDS

Target: TNFRSF19

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-3780

Application*: E, WB

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3779) (CBMAB-T3163-YJ)

SDS

Target: TNFRSF19

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3779

Application*: E

TNFRSF19 Matched Antibody Pair (1230) (APMAB-1230LY)

SDS

Target: TNFRSF19

Specificity: Human

TNFRSF19 Matched Antibody Pair (1229) (APMAB-1229LY)

SDS

Target: TNFRSF19

Specificity: Human

TNFRSF19 Matched Antibody Pair (1228) (APMAB-1228LY)

SDS

Target: TNFRSF19

Specificity: Human

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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