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Mouse Anti-Tnfrsf19 Recombinant Antibody (CBYJT-3792) (CBMAB-T3176-YJ)


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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBYJT-3792
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 197-416 mapping within a C-terminal cytoplasmic domain of TROY of mouse origin
Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 197-416

Target

Full Name
TNFRSF19 Gene(Protein Coding) TNF Receptor Superfamily Member 19
Introduction
Tnfrsf19 can mediate activation of c-Jun and NF-kappa-B. It may promote caspase-independent cell death (By similarity). Isoform 2 and isoform 3 may act as decoy receptors.
Entrez Gene ID
Human55504
Mouse29820
Rat290300
UniProt ID
HumanQ9NS68
MouseQ9JLL3
RatQ1KMU0
Alternative Names
TAJ; Troy; TRADE; AL023044; AW123854; TAJ-ALPHA
Function
Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
Biological Process
Biological Process apoptotic process Source:UniProtKB1 Publication
Biological Process hair follicle development Source:Ensembl
Biological Process JNK cascade Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:GO_Central1 Publication
Biological Process positive regulation of JNK cascade Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Extracellular: 30-170
Helical: 171-191
Cytoplasmic: 192-423
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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