Timd2

Timd2 is a probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation.

T Cell Immunoglobulin And Mucin Domain Containing 2

Cell surface glycoprotein that participates in iron homeostasis in the liver, the kidney, the retina and oligodendrocytes by acting as a receptor of H-ferritin (PubMed:16203866, PubMed:33065090).
Mechanistically, mediates iron-containing ferritin uptake via an endocytic pathway, trafficking to endosomes and subsequently to lysosomes (PubMed:16043519, PubMed:21886823).
Plays also an important role in the regulation of Th2 immunity (PubMed:16043519).
Receptor for SEMA4A involved in the regulation of T-cell function, enhancing T-cell activation (PubMed:12374982).

Biological Process iron ion transportSource:MGI1 Publication
Biological Process phagocytosis, engulfmentSource:GO_Central1 Publication
Biological Process positive regulation of mast cell activationSource:GO_Central1 Publication

Cell membrane

Extracellular: 22-231
Helical: 232-252
Cytoplasmic: 253-305