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ST13

The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Full Name

ST13, Hsp70 Interacting Protein

Function

One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity).

Biological Process

Biological Process chaperone cofactor-dependent protein refoldingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein foldingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process response to bacteriumIEA:Ensembl

Cellular Location

Cytoplasm

Anti-ST13 antibodies

Mouse Anti-ST13 Recombinant Antibody (CBXS-4758) (CBMAB-S1987-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4758

Application*: E, P, WB

Mouse Anti-ST13 Recombinant Antibody (CBXS-5488) (CBMAB-S2697-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5488

Application*: E, IF, IH, WB

Mouse Anti-ST13 Recombinant Antibody (CBXS-6108) (CBMAB-S2943-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXS-6108

Application*: E, WB, IH

Mouse Anti-ST13 Recombinant Antibody (CBXS-6121) (CBMAB-S2956-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXS-6121

Application*: E, WB

Mouse Anti-ST13 Recombinant Antibody (CBXS-0741) (CBMAB-S3671-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-0741

Application*: E, WB

Mouse Anti-ST13 Recombinant Antibody (CBXS-0742) (CBMAB-S3672-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXS-0742

Application*: IP, WB

Mouse Anti-ST13 Recombinant Antibody (CBXS-0743) (CBMAB-S3673-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-0743

Application*: SE, E, WB

Mouse Anti-ST13 Recombinant Antibody (CBXS-2471) (CBMAB-S5228-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: CBXS-2471

Application*: E, IH, WB

Mouse Anti-ST13 Recombinant Antibody (CBXS-2649) (CBMAB-S5402-CQ)

SDS

Target: ST13

Host: Mouse

Specificity: Human

Clone: CBXS-2649

Application*: E, IH, WB

Mouse Anti-ST13 Recombinant Antibody (2B2) (CBMAB-A8622-LY)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2B2

Application*: WB, E

Mouse Anti-ST13 Recombinant Antibody (3B10) (CBMAB-AO989LY)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: 3B10

Application*: WB, IF, IHC

Mouse Anti-ST13 (AA 1-369) Recombinant Antibody (CBFYH-2784) (CBMAB-H0390-FY)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYH-2784

Application*: WB, E, IH, P

Mouse Anti-ST13 Recombinant Antibody (CBFYH-2783) (CBMAB-H0445-FY)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG

Specificity: Chicken, Human, Mouse, Rabbit

Clone: CBFYH-2783

Application*: F, IC, IF, IP, WB

Mouse Anti-ST13 Monoclonal Antibody (CBFYH-3310) (CBMAB-H3851-FY)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat, Monkey

Clone: CBFYH-3310

Application*: WB, IP

Mouse Anti-ST13 (AA 1-369) Recombinant Antibody (AT1F1) (CBMAB-H3852-FY)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: AT1F1

Application*: E, IH, WB

Rabbit Anti-ST13 Recombinant Antibody (CBFYH-2785) (CBMAB-H3854-FY)

SDS

Target: ST13

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Human

Clone: CBFYH-2785

Application*: WB, P, IC, F

Mouse Anti-ST13 Recombinant Antibody (CBXS-4384) (CBMAB-S1627-CQ)

SDS

Target: ST13

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4384

Application*: E, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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