SLC1A6

SLC1A6 functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. SLC1A6 plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate.

solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7791878, PubMed:26690923).
Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport (PubMed:7791878).
Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable).

Biological Process aspartate transmembrane transportManual Assertion Based On ExperimentTAS:ProtInc
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process establishment of localization in cellIEA:Ensembl
Biological Process ion transportTAS:Reactome
Biological Process L-aspartate import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-glutamate import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-glutamate transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neurotransmitter transportTAS:Reactome
Biological Process neurotransmitter uptakeManual Assertion Based On ExperimentIMP:SynGO
Biological Process regulation of membrane potentialIEA:Ensembl

Cell membrane