Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-SLC1A6 Recombinant Antibody (CBFYE-1649) (CBMAB-E2317-FY)


See all SLC1A6 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-1649
Application
WB, IP, ELISA

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Introduction
The animal model revealed suppression of SLC1A6 by clozapine.
Entrez Gene ID
6511
UniProt ID
P48664
Alternative Names
Solute Carrier Family 1 Member 6; Solute Carrier Family 1 (High Affinity Aspartate/Glutamate Transporter), Member 6; Sodium-Dependent Glutamate/Aspartate Transporter; EAAT4; Excitatory Amino Acid Transporter 4
Function
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7791878, PubMed:26690923).
Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport (PubMed:7791878).
Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable).
Biological Process
Biological Process aspartate transmembrane transportManual Assertion Based On ExperimentTAS:ProtInc
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process establishment of localization in cellIEA:Ensembl
Biological Process ion transportTAS:Reactome
Biological Process L-aspartate import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-glutamate import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-glutamate transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neurotransmitter transportTAS:Reactome
Biological Process neurotransmitter uptakeManual Assertion Based On ExperimentIMP:SynGO
Biological Process regulation of membrane potentialIEA:Ensembl
Cellular Location
Cell membrane
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-SLC1A6 Recombinant Antibody (CBFYE-1649)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quoteOnline Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry