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SELL

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
Full Name
Selectin L
Alternative Names
Selectin L; Leukocyte-Endothelial Cell Adhesion Molecule 1; CD62 Antigen-Like Family Member L; Leukocyte Surface Antigen Leu-8; Lymphocyte Adhesion Molecule 1; Lymph Node Homing Receptor; Gp90-MEL; LECAM1; LYAM1; LNHR; TQ1;
Function
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641).
Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641).
Biological Process
Biological Process calcium-dependent cell-cell adhesion via plasma membrane cell adhesion moleculesManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process leukocyte cell-cell adhesionManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process leukocyte tethering or rollingManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 39-332
Helical: 333-355
Cytoplasmic: 356-372
PTM
N-glycosylated.

Anti-SELL antibodies

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Mouse Anti-SELL Recombinant Antibody (AG168) (V2LY-0524-LY33)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AG168
Application*: B, F, IF, C, WB

Rat Anti-SELL Recombinant Antibody (AG169) (V2LY-0524-LY112)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: AG169
Application*: B, MC, F, C, IP, WB

Rat Anti-SELL Recombinant Antibody (A1423) (CBMAB-AP11428LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: A1423
Application*: FC, IHC, IP

Rat Anti-SELL Recombinant Antibody (A1422) (CBMAB-AP12115LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: A1422
Application*: FC, IHC, IP

Mouse Anti-SELL Recombinant Antibody (A1421) (CBMAB-AP10741LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1421
Application*: FC, WB

Mouse Anti-SELL Recombinant Antibody (CB358) (CBMAB-CS358LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB358
Application*: IF, FC

Mouse Anti-SELL Recombinant Antibody (CB357) (CBMAB-CS357LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB357
Application*: IF, FC

Mouse Anti-SELL Recombinant Antibody (CB356) (CBMAB-CS356LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB356
Application*: IF, FC

Rat Anti-SELL Recombinant Antibody (MAB0824) (CBMAB-C12389-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: MAB0824
Application*: F

Mouse Anti-SELL Recombinant Antibody (3H1613) (CBMAB-C12383-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: 3H1613
Application*: F

Mouse Anti-SELL Recombinant Antibody (SK11) (CBMAB-C12387-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Baboon, Chimpanzee, Monkey, Human
Clone: SK11
Application*: F

Mouse Anti-SELL Recombinant Antibody (HI62L) (CBMAB-BC0068-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: HI62L
Application*: E, WB

Mouse Anti-SELL Recombinant Antibody (5F51) (CBMAB-C4254-CN)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5F51
Application*: FC, IF

Mouse Anti-SELL Recombinant Antibody (13A163) (CBMAB-C4253-CN)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 13A163
Application*: FC

Sheep Anti-SELL Recombinant Antibody (12G4) (CBMAB-C4252-CN)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Sheep
Specificity: Human
Clone: 12G4
Application*: E, DB, IH, WB

Mouse Anti-SELL Recombinant Antibody (6D41) (CBMAB-C0322-CN)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6D41
Application*: E, FC, IH

Mouse Anti-SELL Recombinant Antibody (CBWJC-4423) (CBMAB-C5808WJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4423
Application*: F, IH

Mouse Anti-SELL Recombinant Antibody (CBWJC-4422) (CBMAB-C5807WJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4422
Application*: F

Mouse Anti-SELL Recombinant Antibody (CBWJC-4421) (CBMAB-C5806WJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4421
Application*: E, F, FN, WB

Armenian Hamster Anti-SELL Recombinant Antibody (CBWJC-2397) (CBMAB-C3397WJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Armenian Hamster
Antibody Isotype: IgG2, λ
Specificity: Rat
Clone: CBWJC-2397
Application*: F

Mouse Anti-SELL Recombinant Antibody (CBWJC-2396) (CBMAB-C3396WJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJC-2396
Application*: E, F

Mouse Anti-SELL Recombinant Antibody (DREG-56) (CBMAB-C3394WJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: DREG-56
Application*: F, FN, C, N, WB

Mouse Anti-SELL Recombinant Antibody (CBWJC-2395) (CBMAB-C3393WJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2395
Application*: E, F, P

Mouse Anti-SELL Recombinant Antibody (B-S13) (CBMAB-C3391WJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-S13
Application*: E, F

Mouse Anti-SELL Recombinant Antibody (HI62L) (CBMAB-S6358-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: HI62L
Application*: E, F

Mouse Anti-SELL Recombinant Antibody (FMC46) (CBMAB-S6328-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: FMC46
Application*: F, C, IP

Mouse Anti-SELL Recombinant Antibody (CC32) (CBMAB-S6289-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle
Clone: CC32
Application*: F

Rat Anti-SELL Recombinant Antibody (CBXS-5483) (CBMAB-S2693-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBXS-5483
Application*: F, IH, IP

Mouse Anti-SELL Recombinant Antibody (CBXS-5928) (CBMAB-S0777-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5928
Application*: E, WB, IF

Mouse Anti-SELL Recombinant Antibody (CBXS-4215) (CBMAB-S0465-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4215
Application*: F

Mouse Anti-SELL Recombinant Antibody (LAM1-116) (CBMAB-S0436-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: LAM1-116
Application*: F, FN

Mouse Anti-SELL Recombinant Antibody (OX-85) (CBMAB-S0339-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: OX-85
Application*: F

Human Anti-SELL Recombinant Antibody (CBXC-0898) (CBMAB-C4436-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0898
Application*: F

Mouse Anti-SELL Recombinant Antibody (CBXC-1859) (CBMAB-C4435-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1859
Application*: F, E

Mouse Anti-SELL Recombinant Antibody (LT-TD180) (CBMAB-C4434-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: LT-TD180
Application*: F

Rat Anti-SELL Recombinant Antibody (CBXC-1477) (CBMAB-C3373-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXC-1477
Application*: F, IP, WB

Mouse Anti-SELL Recombinant Antibody (CBXC-2416) (CBMAB-C1654-CQ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2416
Application*: F

Rabbit Anti-SELL Recombinant Antibody (CBFYC-3100) (CBMAB-C3177-FY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-3100
Application*: P

Rat Anti-SELL Recombinant Antibody (CBFYC-3099) (CBMAB-C3176-FY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-3099
Application*: F, IH

Sheep Anti-SELL (AA 39-332) Recombinant Antibody (CBFYC-3098) (CBMAB-C3175-FY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Sheep
Specificity: Human
Clone: CBFYC-3098
Application*: E, DB, IH, WB

Mouse Anti-SELL Recombinant Antibody (CBFYC-0409) (CBMAB-C0451-FY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0409
Application*: FN, F

Mouse Anti-SELL Recombinant Antibody (CBFYC-0169) (CBMAB-C0192-FY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle
Clone: CBFYC-0169
Application*: F

Mouse Anti-SELL Recombinant Antibody (CBFYC-0080) (CBMAB-C0090-FY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0080
Application*: F

Mouse Anti-SELL Recombinant Antibody (CBFYC-0067) (CBMAB-C0075-FY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0067
Application*: E, F

Rabbit Anti-SELL Recombinant Antibody (122) (CBMAB-C2581-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 122
Application*: P

Rabbit Anti-SELL Recombinant Antibody (023) (CBMAB-C1683-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 023
Application*: E, EC

Rabbit Anti-SELL Recombinant Antibody (414) (CBMAB-C1271-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 414
Application*: IC/IF, IF

Mouse Anti-SELL Recombinant Antibody (3H1611) (CBMAB-C1188-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Cattle, Human, Monkey
Clone: 3H1611
Application*: F, IH, IP

Mouse Anti-SELL Recombinant Antibody (10B1874) (CBMAB-C0152-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle
Clone: 10B1874
Application*: F

Sheep Anti-SELL Recombinant Antibody (CBYCL-633) (CBMAB-L0534-YC)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Sheep
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-633
Application*: E, WB, DB, IH

Rat Anti-SELL Recombinant Antibody (CBYCL-632) (CBMAB-L0533-YC)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYCL-632
Application*: F, C, IP, BL

Mouse Anti-Sell Recombinant Antibody (CBYJL-2475) (CBMAB-L2855-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: CBYJL-2475
Application*: FC

Mouse Anti-Sell Recombinant Antibody (CBYJL-2474) (CBMAB-L2854-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBYJL-2474
Application*: WB, EC

Mouse Anti-Sell Recombinant Antibody (IVA94) (CBMAB-L2726-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle
Clone: IVA94
Application*: FC

Rat Anti-Sell Recombinant Antibody (MEL-14) (CBMAB-L2725-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: MEL-14
Application*: FC

Rat Anti-Sell Recombinant Antibody (MAB0709) (CBMAB-L2724-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: MAB0709
Application*: P, FC

Rat Anti-Sell Recombinant Antibody (AP-MAB0709) (CBMAB-L2723-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: AP-MAB0709
Application*: FC, P

Rat Anti-Sell Recombinant Antibody (CBYJL-2402) (CBMAB-L2720-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJL-2402
Application*: FC

Mouse Anti-SELL Recombinant Antibody (CBYJL-281) (CBMAB-L0399-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-281
Application*: F

Mouse Anti-SELL Recombinant Antibody (CBYJL-280) (CBMAB-L0398-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Cattle, Dog
Clone: CBYJL-280
Application*: F, IH, C

Mouse Anti-SELL Recombinant Antibody (DREG56) (CBMAB-L0397-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: DREG56
Application*: F

Mouse Anti-SELL Recombinant Antibody (CBYJL-278) (CBMAB-L0395-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-278
Application*: WB, F, E, IH

Mouse Anti-SELL Recombinant Antibody (CBYJL-277) (CBMAB-L0394-YJ)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-277
Application*: F

Mouse Anti-SELL Recombinant Antibody (7H203) (CBMAB-C8814-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 7H203
Application*: F

Rabbit Anti-SELL Recombinant Antibody (18) (CBMAB-C3441-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 18
Application*: E

sheep Anti-SELL Recombinant Antibody (12G5) (CBMAB-C2655-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: sheep
Antibody Isotype: IgG
Specificity: Human
Clone: 12G5
Application*: E, DB, C, WB

sheep Anti-SELL Recombinant Antibody (12G3) (CBMAB-C2652-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: sheep
Antibody Isotype: IgG
Specificity: Human
Clone: 12G3
Application*: E, DB, C, WB

Rabbit Anti-SELL Recombinant Antibody (037) (CBMAB-C1730-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 037
Application*: EC

Rabbit Anti-SELL Recombinant Antibody (018) (CBMAB-C1644-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 018
Application*: E, ED

Mouse Anti-SELL Recombinant Antibody (01) (CBMAB-C0039-LY)

Datasheet Datasheet SDS SDS
Target: SELL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 01
Application*: E, F
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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