OTX1

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy. [provided by RefSeq]

Full Name

orthodenticle homeobox 1

Function

Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.

Biological Process

Anterior/posterior pattern specificationIEA:Ensembl
Diencephalon morphogenesisIEA:Ensembl
Inner ear morphogenesisIEA:Ensembl
Metencephalon developmentIEA:Ensembl
Midbrain developmentIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

Anti-OTX1 antibodies

Mouse Anti-OTX1 Antibody (Otx-5F5) (CBMAB-0881-YC)

Datasheet

SDS

Target: OTX1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Rat

Clone: Otx-5F5

Application*: WB

Mouse Anti-OTX1 (AA 10-116) Recombinant Antibody (3D12) (CBMAB-O0730-CQ)

Datasheet

SDS

Target: OTX1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3D12

Application*: E, IF, WB

Mouse Anti-OTX1 Recombinant Antibody (1F2) (CBMAB-O0731-CQ)

Datasheet

SDS

Target: OTX1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1F2

Application*: E, IF, IR, WB

Mouse Anti-OTX1 Recombinant Antibody (3A5) (CBMAB-O0732-CQ)

Datasheet

SDS

Target: OTX1

Host: Mouse

Specificity: Human

Clone: 3A5

Application*: WB, IP, IF, E

Rabbit Anti-OTX1 Recombinant Antibody (CBXO-0155) (CBMAB-O0733-CQ)

Datasheet

SDS

Target: OTX1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBXO-0155

Application*: WB

Mouse Anti-OTX1 Recombinant Antibody (4E5) (CBMAB-A6263-LY)

Datasheet

SDS

Target: OTX1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4E5

Application*: WB, E

Rabbit Anti-OTX1 Recombinant Antibody (BA0333) (CBMAB-0560CQ)

Datasheet

SDS

Target: OTX1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: BA0333

Application*: WB

Rabbit Anti-OTX1 Recombinant Antibody (BA0236) (CBMAB-0561CQ)

Datasheet

SDS

Target: OTX1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: BA0236

Application*: CI, P, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)