MTHFD1L

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

Full Name

Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1 Like

Function

May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2.

Biological Process

10-formyltetrahydrofolate biosynthetic process Source: BHF-UCL
Embryonic neurocranium morphogenesis Source: BHF-UCL
Embryonic viscerocranium morphogenesis Source: BHF-UCL
Folic acid-containing compound metabolic process Source: BHF-UCL
Formate metabolic process Source: BHF-UCL
Neural tube closure Source: BHF-UCL
Tetrahydrofolate interconversion Source: GO_Central

Cellular Location

Mitochondrion

Anti-MTHFD1L antibodies

Mouse Anti-MTHFD1L Recombinant Antibody (1E8) (CBMAB-A5661-LY)

Datasheet

SDS

Target: MTHFD1L

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Rat

Clone: 1E8

Application*: WB, E

Mouse Anti-MTHFD1L (AA 801-900) Recombinant Antibody (CBFYM-2737) (CBMAB-M2930-FY)

Datasheet

SDS

Target: MTHFD1L

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-2737

Application*: WB

Mouse Anti-MTHFD1L (AA 801-900) Recombinant Antibody (CBXF-1011) (CBMAB-F0309-CQ)

Datasheet

SDS

Target: MTHFD1L

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXF-1011

Application*: E, WB

Rabbit Anti-MTHFD1L Recombinant Antibody (D8T7L ) (CBMAB-CP1597-LY)

Datasheet

SDS

Target: MTHFD1L

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: D8T7L

Application*: WB

Rabbit Anti-MTHFD1L Recombinant Antibody (D7O8E ) (CBMAB-CP1598-LY)

Datasheet

SDS

Target: MTHFD1L

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: D7O8E

Application*: WB, IP

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)