METAP1D

The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases.

Full Name

METHIONYL AMINOPEPTIDASE TYPE 1D, MITOCHONDRIAL

Function

Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity).

May play a role in colon tumorigenesis.

Biological Process

N-terminal protein amino acid modification Source: HGNC-UCL
Peptidyl-methionine modification Source: HGNC-UCL
Protein initiator methionine removal Source: UniProtKB-UniRule

Cellular Location

Mitochondrion

Anti-METAP1D antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Rabbit Anti-METAP1D (AA 44-335) Recombinant Antibody (CBFYM-2111) (CBMAB-M2293-FY)

Datasheet

SDS

Target: METAP1D

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYM-2111

Application*: E

Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2110) (CBMAB-M2292-FY)

Datasheet

SDS

Target: METAP1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-2110

Application*: E, WB

Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2109) (CBMAB-M2291-FY)

Datasheet

SDS

Target: METAP1D

Host: Mouse

Specificity: Human

Clone: CBFYM-2109

Application*: WB, IP, IF, E

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)