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Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2110) (CBMAB-M2292-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2110
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Immunogen
Recombinant human MAP1D protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
METHIONYL AMINOPEPTIDASE TYPE 1D, MITOCHONDRIAL
Introduction
The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases .
Entrez Gene ID
254042
UniProt ID
Q6UB28
Alternative Names
Methionyl Aminopeptidase Type 1D, Mitochondrial; Peptidase M 1D; MetAP 1D; MAP 1D; MAP1D; Methionine Aminopeptidase 1D, Mitochondrial
Function
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity).

May play a role in colon tumorigenesis.
Biological Process
N-terminal protein amino acid modification Source: HGNC-UCL
Peptidyl-methionine modification Source: HGNC-UCL
Protein initiator methionine removal Source: UniProtKB-UniRule
Cellular Location
Mitochondrion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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