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LRRFIP1

LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. It may control smooth muscle cells proliferation following artery injury through PDGFA repression. It may also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

Full Name

LRRFIP1

Function

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

Biological Process

Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus
Cytoplasm

Anti-LRRFIP1 antibodies

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYJT-1421) (CBMAB-T0445-YJ)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-1421

Application*: E, IF, WB

Mouse Anti-Lrrfip1 Recombinant Antibody (CBYJL-2590) (CBMAB-L3030-YJ)

SDS

Target: Lrrfip1

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: CBYJL-2590

Application*: WB, IP, IF, E

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYJL-2032) (CBMAB-L2148-YJ)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-2032

Application*: WB, IP, IF, E

Mouse Anti-LRRFIP1 Recombinant Antibody (4F3-D8-C9) (CBMAB-L2147-YJ)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 4F3-D8-C9

Application*: WB

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYJL-2031) (CBMAB-L2146-YJ)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJL-2031

Application*: E, WB

Mouse Anti-LRRFIP1 Recombinant Antibody (3E1) (CBMAB-L2144-YJ)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3E1

Application*: IF, WB

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYJL-2029) (CBMAB-L2143-YJ)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-2029

Application*: E, IF, WB

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYJL-2028) (CBMAB-L2142-YJ)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJL-2028

Application*: E, IF, IH, WB

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYJL-2027) (CBMAB-L2141-YJ)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: CBYJL-2027

Application*: WB

Mouse Anti-LRRFIP1 Recombinant Antibody (A940) (CBMAB-AP11549LY)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: A940

Application*: WB

Mouse Anti-LRRFIP1 Recombinant Antibody (A939) (CBMAB-AP4318LY)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: A939

Application*: ELISA, WB

Mouse Anti-LRRFIP1 Recombinant Antibody (2D3) (CBMAB-A5075-LY)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2D3

Application*: WB, E

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYCL-486) (CBMAB-L0387-YC)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: CBYCL-486

Application*: E, WB

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYCL-485) (CBMAB-L0386-YC)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYCL-485

Application*: WB, E, P, F, IC, IF

Mouse Anti-LRRFIP1 Recombinant Antibody (CBYCL-484) (CBMAB-L0385-YC)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: CBYCL-484

Application*: WB

Mouse Anti-LRRFIP1 Antibody (3A8) (CBMAB-0627-YC)

SDS

Target: LRRFIP1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 3A8

Application*: IP, M

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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