LRIG1

Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

Full Name

leucine rich repeats and immunoglobulin like domains 1

Function

Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

Biological Process

Hair cycle processIEA:Ensembl
InnervationIEA:Ensembl
Otolith morphogenesisIEA:Ensembl
Sensory perception of soundIEA:Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 35-794
Helical: 795-815
Cytoplasmic: 816-1093

Anti-LRIG1 antibodies

Rat Anti-Lrig1 Recombinant Antibody (CBYJL-2384) (CBMAB-L2695-YJ)

Datasheet

SDS

Target: Lrig1

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBYJL-2384

Application*: B

Mouse Anti-LRIG1 Recombinant Antibody (CBYJL-1955) (CBMAB-L2022-YJ)

Datasheet

SDS

Target: LRIG1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-1955

Application*: WB, IP, IF, E

Mouse Anti-LRIG1 Recombinant Antibody (CBYJL-1954) (CBMAB-L2021-YJ)

Datasheet

SDS

Target: LRIG1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJL-1954

Application*: F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)