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LGALS1

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.
Full Name
LGALS1
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Biological Process
Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Cell-cell adhesionManual Assertion Based On ExperimentIDA:ComplexPortal
Myoblast differentiationIEA:Ensembl
Plasma cell differentiationIEA:Ensembl
Positive regulation of apoptotic processManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of I-kappaB kinase/NF-kappaB signalingManual Assertion Based On ExperimentHMP:UniProtKB
Positive regulation of inflammatory responseManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of viral entry into host cellManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of apoptotic processManual Assertion Based On ExperimentTAS:UniProtKB
T cell costimulationIEA:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
Cytoplasm
Secreted
Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.

Anti-LGALS1 antibodies

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Rabbit Anti-LGALS1 Recombinant Antibody (CBLG1-2335) (CBMAB-G6209-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2335
Application*: E, ED

Rabbit Anti-LGALS1 Recombinant Antibody (CBLG1-2334) (CBMAB-G6208-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2334
Application*: WB

Mouse Anti-LGALS1 Recombinant Antibody (CBLG1-2333) (CBMAB-G6207-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBLG1-2333
Application*: E (IA), WB

Mouse Anti-LGALS1 Recombinant Antibody (CBLG1-2332) (CBMAB-G6206-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2332
Application*: WB

Mouse Anti-LGALS1 Recombinant Antibody (CBLG1-2331) (CBMAB-G6205-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2331
Application*: P

Mouse Anti-LGALS1 Recombinant Antibody (CBLG1-2330) (CBMAB-G6204-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2330
Application*: E, WB

Mouse Anti-LGALS1 Recombinant Antibody (CBLG1-2340) (CBMAB-G6214-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBLG1-2340
Application*: E

Mouse Anti-LGALS1 Recombinant Antibody (CBLG1-2339) (CBMAB-G6213-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2339
Application*: E

Rabbit Anti-LGALS1 Recombinant Antibody (CBLG1-2337) (CBMAB-G6211-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2337
Application*: EC

Rabbit Anti-LGALS1 Recombinant Antibody (1) (CBMAB-G6186-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 1
Application*: WB

Rabbit Anti-LGALS1 Recombinant Antibody (SP247) (CBMAB-G1100-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Cattle, Human, Mouse, Pig, Rat
Clone: SP247
Application*: F

Rabbit Anti-LGALS1 Recombinant Antibody (CBLG1-3071) (CBMAB-G1098-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-3071
Application*: IC

Mouse Anti-Lgals1 Recombinant Antibody (CBYJL-2449) (CBMAB-L2807-YJ)

Datasheet Datasheet SDS SDS
Target: Lgals1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBYJL-2449
Application*: E

Mouse Anti-Lgals1 Recombinant Antibody (CBYJL-2448) (CBMAB-L2806-YJ)

Datasheet Datasheet SDS SDS
Target: Lgals1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBYJL-2448
Application*: E, WB

Rat Anti-Lgals1 Recombinant Antibody (CBYJL-2447) (CBMAB-L2805-YJ)

Datasheet Datasheet SDS SDS
Target: Lgals1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJL-2447
Application*: C, WB

Rabbit Anti-LGALS1 (C-terminus) Monoclonal Antibody (CBFYH-3287) (CBMAB-H3652-FY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Cattle, Human, Mouse, Pig, Rat
Clone: CBFYH-3287
Application*: F, WB, P

Mouse Anti-LGALS1 Recombinant Antibody (CBFYH-2615) (CBMAB-H3653-FY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2615
Application*: P, WB

Mouse Anti-LGALS1 (AA 1-135) Recombinant Antibody (CBFYH-2616) (CBMAB-H3654-FY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2616
Application*: WB, IH

Mouse Anti-LGALS1 Recombinant Antibody (CBLG1-2329) (CBMAB-G6203-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBLG1-2329
Application*: WB

Mouse Anti-LGALS1 Recombinant Antibody (CBLG1-2328) (CBMAB-G6202-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLG1-2328
Application*: WB

Rat Anti-LGALS1 Recombinant Antibody (RM0081-9J26) (CBMAB-G6200-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: RM0081-9J26
Application*: WB

Rabbit Anti-LGALS1 Recombinant Antibody (D608T) (CBMAB-G6198-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D608T
Application*: P

Rat Anti-LGALS1 Recombinant Antibody (9J26) (CBMAB-G6197-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 9J26
Application*: IH, WB

Rabbit Anti-LGALS1 Recombinant Antibody (8) (CBMAB-G6195-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 8
Application*: E

Mouse Anti-LGALS1 Recombinant Antibody (24CT661.4.3) (CBMAB-G6192-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 24CT661.4.3
Application*: WB

Mouse Anti-LGALS1 Recombinant Antibody (2) (CBMAB-G6190-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2
Application*: WB

Rat Anti-LGALS1 Recombinant Antibody (14L452) (CBMAB-G6188-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 14L452
Application*: IH, WB

Mouse Anti-LGALS1 Recombinant Antibody (10i45) (CBMAB-G6187-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10i45
Application*: E, WB

Mouse Anti-LGALS1 Recombinant Antibody (CBYCL-252) (CBMAB-L0153-YC)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Cattle
Clone: CBYCL-252
Application*: WB, IC, P, C, E

Mouse Anti-LGALS1 Recombinant Antibody (CBYCL-253) (CBMAB-L0154-YC)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-253
Application*: E, IH, WB

Mouse Anti-LGALS1 Recombinant Antibody (CBYCL-254) (CBMAB-L0155-YC)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYCL-254
Application*: WB, IC, P, C, E

Mouse Anti-LGALS1 Recombinant Antibody (CBYCL-255) (CBMAB-L0156-YC)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYCL-255
Application*: E, IC, WB

Rat Anti-Lgals1 Recombinant Antibody (CBYJL-2446) (CBMAB-L2803-YJ)

Datasheet Datasheet SDS SDS
Target: Lgals1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJL-2446
Application*: WB, IH

Mouse Anti-LGALS1 (AA 12-108) Recombinant Antibody (GAL1/1831) (CBMAB-H0127-FY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1, λ
Specificity: Human
Clone: GAL1/1831
Application*: WB, F, E, IF, P, MC

Rabbit Anti-LGALS1 Recombinant Antibody (CBYJL-1490) (CBMAB-L1230-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1490
Application*: IP, WB

Mouse Anti-LGALS1 Recombinant Antibody (1E8-1B2) (CBMAB-L1231-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Human
Clone: 1E8-1B2
Application*: E, IF, IP, WB

Mouse Anti-LGALS1 Recombinant Antibody (CBYJL-1491) (CBMAB-L1232-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1491
Application*: E, WB, P, F

Mouse Anti-LGALS1 Recombinant Antibody (CBYJL-1492) (CBMAB-L1233-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1492
Application*: IP, WB

Mouse Anti-LGALS1 Recombinant Antibody (24CT661-4-3) (CBMAB-L1234-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 24CT661-4-3
Application*: P, WB

Mouse Anti-LGALS1 Recombinant Antibody (24CT661-4-4) (CBMAB-L1235-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 24CT661-4-4
Application*: E, WB

Mouse Anti-LGALS1 Recombinant Antibody (6C8.4-1) (CBMAB-L1237-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6C8.4-1
Application*: IC, IF, WB

Rabbit Anti-LGALS1 Recombinant Antibody (CBYJL-1494) (CBMAB-L1238-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1494
Application*: E

Rabbit Anti-LGALS1 Recombinant Antibody (CBYJL-1495) (CBMAB-L1239-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1495
Application*: IC, P, IP, WB

Mouse Anti-LGALS1 Recombinant Antibody (CBYJL-1496) (CBMAB-L1240-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1, λ
Specificity: Human
Clone: CBYJL-1496
Application*: E, WB, P, IF, IC, F

Mouse Anti-LGALS1 Recombinant Antibody (CBYJL-1497) (CBMAB-L1241-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1497
Application*: E

Mouse Anti-LGALS1 Recombinant Antibody (CBYJL-1499) (CBMAB-L1243-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBYJL-1499
Application*: E, F

Rabbit Anti-LGALS1 Recombinant Antibody (CBYJL-1500) (CBMAB-L1244-YJ)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1500
Application*: P

Mouse Anti-LGALS1 Recombinant Antibody (1A8) (CBMAB-A4937-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Human
Clone: 1A8
Application*: WB, E

Mouse Anti-LGALS1 Recombinant Antibody (8A12) (CBMAB-CP0793-LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8A12
Application*: WB, P

Mouse Anti-LGALS1 Recombinant Antibody (CF267) (CBMAB-FT299LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF267
Application*: ELISA, WB, IHC

Mouse Anti-LGALS1 Recombinant Antibody (214) (CBMAB-AP2984LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 214
Application*: ELISA, IHC, WB

LGALS1 Matched Antibody Pair (687) (APMAB-687LY)

Datasheet Datasheet SDS SDS
Target: LGALS1
Specificity: Human
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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