LCOR

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor box.

Full Name

LCOR

Function

May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity).
Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR.

Biological Process

Cellular response to estradiol stimulusManual Assertion Based On ExperimentIDA:ARUK-UCL
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:ARUK-UCL
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

Anti-LCOR antibodies

Mouse Anti-LCOR Antibody (1A7) (CBMAB-0608-YC)

Datasheet

SDS

Target: LCOR

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1A7

Application*: IP, M

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1303) (CBMAB-L0884-YJ)

Datasheet

SDS

Target: LCOR

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJL-1303

Application*: WB

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1305) (CBMAB-L0886-YJ)

Datasheet

SDS

Target: LCOR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-1305

Application*: WB

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1307) (CBMAB-L0888-YJ)

Datasheet

SDS

Target: LCOR

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJL-1307

Application*: IC, IF

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1308) (CBMAB-L0889-YJ)

Datasheet

SDS

Target: LCOR

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBYJL-1308

Application*: WB, IP, IF, E

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1310) (CBMAB-L0891-YJ)

Datasheet

SDS

Target: LCOR

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-1310

Application*: WB, IP, IF, E

Mouse Anti-LCOR (AA 204-433) Recombinant Antibody (CBFYM-1209) (CBMAB-M1366-FY)

Datasheet

SDS

Target: LCOR

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYM-1209

Application*: WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)