LACTB2

Gene Ontology (GO) annotations related to LACTB2 include hydrolase activity. LACTB2 cleaves preferentially 3 to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3 -OH group. LACTB2 has no activity with double-stranded RNA or DNA. LACTB2 is required for normal mitochondrial function and cell viability.

Full Name

lactamase, beta 2

Function

Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

Biological Process

RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Mitochondrion matrix

Anti-LACTB2 antibodies

Mouse Anti-LACTB2 Recombinant Antibody (4F7) (CBMAB-L0464-YJ)

Datasheet

SDS

Target: LACTB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4F7

Application*: WB

Mouse Anti-LACTB2 Recombinant Antibody (4E7) (CBMAB-L0463-YJ)

Datasheet

SDS

Target: LACTB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4E7

Application*: F, WB

Mouse Anti-LACTB2 Recombinant Antibody (3A5) (CBMAB-L0462-YJ)

Datasheet

SDS

Target: LACTB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3A5

Application*: F, IH, WB

Mouse Anti-LACTB2 Recombinant Antibody (2F9) (CBMAB-L0461-YJ)

Datasheet

SDS

Target: LACTB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2F9

Application*: F, P, WB

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1046) (CBMAB-L0460-YJ)

Datasheet

SDS

Target: LACTB2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJL-1046

Application*: E, WB

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1045) (CBMAB-L0459-YJ)

Datasheet

SDS

Target: LACTB2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJL-1045

Application*: F, P, WB

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1044) (CBMAB-L0458-YJ)

Datasheet

SDS

Target: LACTB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-1044

Application*: WB, F

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)