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Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1046) (CBMAB-L0460-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-1046
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
LACTB2 (NP_057111.1, 1 a.a. ~ 288 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MAAVLQRVER LSNRVVRVLG CNPGPMTLQG TNTYLVGTGP RRILIDTGEP AIPEYISCLK QALTEFNTAI QEIVVTHWHR DHSGGIGDIC KSINNDTTYC IKKLPRNPQR EEIIGNGEQQ YVYLKDGDVI KTEGATLRVL YTPGHTDDHM ALLLEEENAI FSGDCILGEG TTVFEDLYDY MNSLKELLKI KADIIYPGHG PVIHNAEAKI QQYISHRNIR EQQILTLFRE NFEKSFTVME LVKIIYKNTP ENLHEMAKHN LLLHLKKLEK EGKIFSNTDP DKKWKAHL.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-288

Target

Full Name
lactamase, beta 2
Introduction
Gene Ontology (GO) annotations related to LACTB2 include hydrolase activity. LACTB2 cleaves preferentially 3 to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3 -OH group. LACTB2 has no activity with double-stranded RNA or DNA. LACTB2 is required for normal mitochondrial function and cell viability.
Entrez Gene ID
51110
UniProt ID
Q53H82
Function
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
Biological Process
RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Mitochondrion matrix
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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