INA

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.

Full Name

internexin neuronal intermediate filament protein alpha

Function

Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).

Biological Process

Cell differentiationIEA:UniProtKB-KW
Cellular response to leukemia inhibitory factorIEA:Ensembl
Neurofilament cytoskeleton organizationIEA:Ensembl
Substantia nigra developmentManual Assertion Based On ExperimentHEP:UniProtKB

Cellular Location

Cytoplasmic ribonucleoprotein granule; Extracellular space; Neurofilament; Postsynapse; Schaffer collateral - CA1 synapse

PTM

O-glycosylated.

Anti-INA antibodies

Rabbit Anti-INA Recombinant Antibody (9i172) (CBMAB-I1843-YY)

Datasheet

SDS

Target: INA

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Rat

Clone: 9i172

Application*: F, IC, IH, IP, WB

Rabbit Anti-INA Recombinant Antibody (EP676Y) (CBMAB-1587-CN)

Datasheet

SDS

Target: INA

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EP676Y

Application*: F, IF, P, IP, WB

Mouse Anti-INA Recombinant Antibody (2E3) (CBMAB-A4484-YC)

Datasheet

SDS

Target: INA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 2E3

Application*: E, F, IC, IF, IH, WB

Mouse Anti-INA Recombinant Antibody (2E4) (CBMAB-A4486-YC)

Datasheet

SDS

Target: INA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat

Clone: 2E4

Application*: WB, IH, IC, IF, P, C

Mouse Anti-INA Recombinant Antibody (7.1.2) (CBMAB-A4487-YC)

Datasheet

SDS

Target: INA

Host: Mouse

Antibody Isotype: IgG, κ

Specificity: Mouse

Clone: 7.1.2

Application*: WB, IC, IF, P

Mouse Anti-INA Recombinant Antibody (ID2) (CBMAB-A4488-YC)

Datasheet

SDS

Target: INA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Cattle, Mouse, Frog

Clone: ID2

Application*: E, IF, WB, IH

Mouse Anti-INA Recombinant Antibody (NF66) (CBMAB-A4489-YC)

Datasheet

SDS

Target: INA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Rat

Clone: NF66

Application*: WB, IH, IC, IF, P, IF

Mouse Anti-INA Recombinant Antibody (CBYC-A986) (CBMAB-A4490-YC)

Datasheet

SDS

Target: INA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYC-A986

Application*: WB, IH

Rabbit Anti-INA Recombinant Antibody (EG1653) (CBMAB-EN1978-LY)

Datasheet

SDS

Target: INA

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1653

Application*: WB: 1:500~1:1000 ELISA: 1:40000

Mouse Anti-INA Recombinant Antibody (257CT7.1.2) (CBMAB-I0641-YY)

Datasheet

SDS

Target: INA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse

Clone: 257CT7.1.2

Application*: WB, P, IF, E, IC, IH

Mouse Anti-INA Recombinant Antibody (CBYY-I0245) (CBMAB-I0642-YY)

Datasheet

SDS

Target: INA

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I0245

Application*: IF, P, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)